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UDP-N-Acetylgalactosamine

sodium salt, lyophilizate

For further processing only.

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Order information
UDP-N-Acetylgalactosamine material number and pack size:
Material Number Pack Size
06369855103 custom fill
Unit of measure is "gram".
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Overview
UDP-N-Acetylgalactosamine is an activated sugar, and can be used for in vitro glycoengineering of glycoproteins, e.g. therapeutic proteins.
UDP-N-Acetylgalactosamine is a disodium salt, provided as a white, lyophilized substance.
Benefits of using in vitro glycoengineering to modify glycosylation of therapeutic proteins:
  • Time- and cost-saving generation of glycan variants to develop improved drugs
  • Optimized glycosylation without compromising other CQAs or product yield
  • Improved lot-to-lot consistency to reduce risk of product quality variation and resulting delays
  • Generation of glycoprofiles which may not otherwise be generated
  • Streamlined analytics in comparability studies
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Application
UDP-N-Acetylgalactosamine can be used for glycosylation of target molecules with a suitable enzyme.
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Specification
Formula: C17H25N3O17P2 Na2
Molar mass:
UDPGalNAc: 607.4 g/mol
UDPGalNAc-Na2: 651.32 g/mol
Appearance: White powder
Solution (c = 100 mg/mL water): Clear, colorless
Identity (1H-NMR): spectrum conforms to reference spectrum.
UDPGalNAc (HPLC), based on dry weight: ≥95%
UDPGalNAc (HPLC): ≥97% area%
Water (K. Fischer): ≤8%
Na (flame photometer): 6.0 - 8.0%
UDPGlucNAc (1H-NMR): ≤1%
UMP (HPLC): ≤1 area%
UDP (HPLC): ≤1 area%
Heavy metals (as Pb): ≤25 ppm
Proteins (Bradford): ≤100 μg/g
Endotoxine: ≤0.5 EU/mg
Bioburden: ≤100 CFU/g
Stability: At +2 to +8°C within specification range for 24 months.
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License disclaimer

50:Use of this product is covered by US patent claims and corresponding patent claims outside the US. The purchase of this product includes a limited, non-transferable immunity from suit under the foregoing patent claims for using only this amount of product solely in [Field], including reporting results of purchaser’s activities for a fee or other commercial consideration, and also for the purchaser’s own internal research. No right under any other patent claim is conveyed expressly, by implication, or by estoppel. Further information on purchasing licenses may be obtained by contacting the Director of Licensing, Applied Biosystems, 850 Lincoln Centre Drive, Foster City, California 94404, USA.